Chicago Rot 2016 focuses on Les, a street legend known as "The Ghoul," who is wrongfully imprisoned for years. Upon his release from Joliet, he embarks on a relentless and brutal search through Chicago's dark underbelly for the man who murdered his mother and stole his soul. Aided by mysterious benefactors, he navigates a supernatural underworld, where the lines between good and evil are blurred, and heroes are transformed into horror-shows. The film blends elements of action, horror, science fiction, and fantasy.